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Ira J Dunkel Selected Research

Thiotepa (Triethylenethiophosphoramide)

11/2022Intensive Multimodality Therapy for Extraocular Retinoblastoma: A Children's Oncology Group Trial (ARET0321).
1/2018Tandem thiotepa with autologous hematopoietic cell rescue in patients with recurrent, refractory, or poor prognosis solid tumor malignancies.
7/2015Pilot Study of Intensive Chemotherapy With Peripheral Hematopoietic Cell Support for Children Less Than 3 Years of Age With Malignant Brain Tumors, the CCG-99703 Phase I/II Study. A Report From the Children's Oncology Group.
4/2010Thiotepa/topotecan/carboplatin with autologous stem cell rescue in recurrent/refractory/poor prognosis pediatric malignancies of the central nervous system.
3/2010High-dose carboplatin, thiotepa, and etoposide with autologous stem cell rescue for patients with previously irradiated recurrent medulloblastoma.
12/2008Myeloablative chemotherapy with autologous bone marrow rescue in children and adolescents with recurrent malignant astrocytoma: outcome compared with conventional chemotherapy: a report from the Children's Oncology Group.
5/2004Thiotepa-based high-dose chemotherapy with autologous stem-cell rescue in patients with recurrent or progressive CNS germ cell tumors.

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Ira J Dunkel Research Topics

Disease

55Neoplasms (Cancer)
10/2022 - 02/2002
51Retinoblastoma (Glioblastoma, Retinal)
11/2022 - 10/2003
14Brain Neoplasms (Brain Tumor)
08/2022 - 02/2002
14Glioma (Gliomas)
08/2022 - 05/2004
14Medulloblastoma
01/2022 - 01/2002
8Germ Cell and Embryonal Neoplasms (Germ Cell Tumor)
09/2017 - 02/2002
6Disease Progression
01/2018 - 01/2007
5Neuroblastoma
10/2022 - 03/2004
4Central Nervous System Neoplasms
01/2021 - 04/2010
4Neutropenia
01/2021 - 08/2010
4Melanoma (Melanoma, Malignant)
11/2020 - 04/2008
4Neoplasm Metastasis (Metastasis)
01/2020 - 07/2010
4Exanthema (Rash)
01/2020 - 11/2017
4Diffuse Intrinsic Pontine Glioma
01/2020 - 07/2017
4Astrocytoma (Pilocytic Astrocytoma)
01/2019 - 10/2006
4Germinoma
04/2016 - 05/2004
3Sepsis (Septicemia)
01/2021 - 03/2010
3Fever (Fevers)
01/2021 - 08/2010
3Langerhans-Cell Histiocytosis (Histiocytosis, Langerhans Cell)
01/2018 - 01/2008
3Retinal Detachment (Retinal Detachments)
01/2018 - 08/2008
3Fatigue
01/2018 - 01/2017
3Residual Neoplasm
01/2018 - 12/2008
3Ependymoma
07/2017 - 10/2007
3Second Primary Neoplasms (Neoplasms, Second)
01/2016 - 10/2007
3Primitive Neuroectodermal Tumors (PNET)
03/2008 - 01/2002
2Rhabdomyosarcoma
10/2022 - 07/2017
2Ewing Sarcoma (Sarcoma, Ewing)
10/2022 - 01/2017
2Sarcoma (Soft Tissue Sarcoma)
11/2020 - 12/2018
2Hemorrhage
01/2020 - 01/2012
2Meningioma (Meningiomas)
08/2016 - 10/2010
2Ototoxicity
04/2013 - 11/2011
2Leukemia
10/2010 - 07/2007
2Diabetes Insipidus
01/2008 - 08/2004
2Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
07/2007 - 03/2004
1Thrombocytopenia (Thrombopenia)
10/2022
113q deletion syndrome
01/2021
1Hypertension (High Blood Pressure)
01/2021
1Leukopenia
01/2021
1Febrile Neutropenia
01/2021
1Craniopharyngioma (Craniopharyngiomas)
11/2020
1Leiomyosarcoma
11/2020
1Nervous System Diseases (Neurological Disorders)
01/2020
1Arthralgia (Joint Pain)
12/2019
1Histiocytosis
12/2019

Drug/Important Bio-Agent (IBA)

18Carboplatin (JM8)FDA LinkGeneric
11/2022 - 10/2003
10Melphalan (Alkeran)FDA LinkGeneric
01/2016 - 08/2008
9Topotecan (Hycamtin)FDA LinkGeneric
01/2014 - 04/2010
7Thiotepa (Triethylenethiophosphoramide)FDA LinkGeneric
11/2022 - 05/2004
7Etoposide (VP 16)FDA LinkGeneric
11/2022 - 03/2004
7Retinaldehyde (Retinal)IBA
01/2018 - 08/2008
6Pharmaceutical PreparationsIBA
12/2019 - 01/2007
5Cyclophosphamide (Cytoxan)FDA LinkGeneric
10/2022 - 08/2004
4dipinacoline glutamateIBA
01/2020 - 01/2017
3AZD 6244IBA
08/2022 - 01/2019
3dabrafenibIBA
12/2019 - 01/2018
3perifosineIBA
07/2017 - 01/2017
3Tumor Biomarkers (Tumor Markers)IBA
05/2014 - 08/2006
3Alkylating AgentsIBA
04/2010 - 02/2002
3Vincristine (Oncovin)FDA LinkGeneric
06/2008 - 01/2007
3Cisplatin (Platino)FDA LinkGeneric
06/2008 - 08/2004
2Cell-Free Nucleic AcidsIBA
10/2022 - 01/2020
2Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
10/2021 - 12/2019
2DNA (Deoxyribonucleic Acid)IBA
01/2021 - 01/2020
2Phosphotransferases (Kinase)IBA
01/2020 - 12/2019
2Proteins (Proteins, Gene)FDA Link
01/2016 - 03/2011
2Carmustine (FIVB)FDA Link
12/2008 - 05/2004
2Monoclonal AntibodiesIBA
12/2008 - 02/2002
2Immunoglobulins (Immunoglobulin)IBA
12/2008 - 02/2002
1serum P-component (CIt)IBA
10/2022
1Doxorubicin (Adriamycin)FDA LinkGeneric
10/2022
1Isotretinoin (Accutane)FDA LinkGeneric
01/2022
1VorinostatFDA Link
01/2022
1Cyclin-Dependent Kinase 4IBA
01/2021
1Retinoblastoma ProteinIBA
01/2021
1Filgrastim (Neupogen)FDA Link
01/2021
1palbociclibIBA
01/2021
1pomalidomideIBA
01/2021
1Alanine Transaminase (SGPT)IBA
01/2021
1ribociclibIBA
01/2021
1EverolimusFDA Link
01/2021
1InterferonsIBA
11/2020
1Temozolomide (Temodar)FDA LinkGeneric
01/2020
1veliparibIBA
01/2020
1tyrosine receptor (receptor, tyrosine)IBA
12/2019
1selpercatinibIBA
12/2019

Therapy/Procedure

55Drug Therapy (Chemotherapy)
11/2022 - 01/2002
28Therapeutics
11/2022 - 03/2004
25Radiotherapy
11/2022 - 02/2002
7Aftercare (After-Treatment)
01/2016 - 08/2008
4Craniospinal Irradiation
09/2017 - 06/2008
3Radioimmunotherapy
01/2018 - 12/2007
3Brachytherapy
11/2013 - 08/2008
2Platelet Transfusion (Blood Platelet Transfusions)
10/2022 - 01/2021
2Adjuvant Chemotherapy
01/2019 - 07/2007
2Salvage Therapy
01/2016 - 11/2012
2Induction Chemotherapy
06/2008 - 03/2008
1Intravitreal Injections
01/2021
1Eye Enucleation (Enucleation, Eye)
01/2020
1Chemoradiotherapy
01/2020
1Duration of Therapy
12/2019